Using her wit and vast knowledge of medicines and poisons alike, Maomao played a pivotal role in solving a series of mysteries and conspiracies that plagued the imperial court. Having recently come to terms with the secrets of her parents, she returns to fulfill her normal duties on behalf of the emperor's highest-ranking consorts. Maomao also works alongside the eunuch Jinshi to better the consorts' many ladies-in-waiting, including helping them learn to read. However, with the arrival of a merchant caravan comes a new wave of intrigue. A pattern of strange coincidences involving the visitors and their wares unsettles Maomao, driving her to investigate the puzzling circumstances behind the convoy. As dangers from both outside and within threaten the balance between the imperial concubines, Maomao continues to utilize her cunning and medical expertise to keep the women safe from harm. [Written by MAL Rewrite]
PG-13 - Teens 13 or older
OLM, TOHO animation STUDIO
Dentsu, Square Enix, Nippon Television Network, TOHO animation, Sound Team Don Juan, Shogakukan, Imagica Infos
Jan 10, 2025 to Jul 4, 2025
Light novel
Jinshi
Main
Maomao
Main
Ah-Duo
Supporting
Ailan
Supporting
Anshi
Supporting
Anshi's Lady-in-waiting
Supporting
Ayla
Supporting
Aylin
Supporting
Basen
Supporting
Emperor
Supporting
Empress Dowager's Sister
Supporting
Empress Regnant
Supporting
Gaoshun
Supporting
Guen
Supporting
Guiyuan
Supporting
Gyokuyou
Supporting
Kusuriya no Hitorigoto 2nd Season aired on Nippon TV's Friday Anime Night block. It was released on Blu-ray in four volumes by Toho from April 16, 2025, to October 15, 2025. The series adapts the third and fourth volume of the light novel.
The Beginning
The Shi Clan
Royal Guard
Taibon
The Stronghold
Festival
Lantern Plant
Fox Village
Festering Resentment
Ice
The Dancing Ghost
The Baths
Ka Zuigetsu
The Hunt
A Ghost Story
The Late Emperor
The Empress Dowager
The Shrine of Choosing
The Crystal Pavilion, For the Third Time
The Moon Fairy
Mirror
Corpse Fungus
Caravan
Maomao and Maomao